
Top 200 Brand and Generic Drugs for 2026 – 2027 Exams.



At a glance.
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Top 200 Drugs
- There is no single official Top 200 Drugs list. The medications included in this list can vary by year and source. Our Top 200 Drugs list is updated annually to reflect these changes. You can find our latest list of medicines below.
- For each drug, learn its generic name, common brand name, therapeutic class, primary indication, major side effects, and important interactions. Avoid studying drug strengths, dosing, and detailed mechanisms of action.
- Recognizing common drug suffixes—such as -pril, -sartan, -statin, and -prazole—can make medication classes easier to identify.
- Suffixes are useful learning clues but they are not universal rules. Some drugs do not follow the usual naming pattern.
- Remember – pharmacy technicians should understand medications by class and clinical use instead of relying only on memorized name pairs. Focus on high-yield clinical details that get tested.
- Routine study with flashcards, quizzes, and spaced review can improve long-term recall. Avoid rushing to learn the Top 200 drugs, this creates confusion and worsens retention.
How to learn the Top 200 drugs.
Learning the Top 200 brand and generic drugs can initially feel overwhelming. Some medicines contain multiple active ingredients, individual drugs may have several brand names, and many names appear to have little connection with their therapeutic use. The multiple-choice format of the PTCE can work in your favor, however. You do not always need to recall a drug name without assistance; you may instead need to recognize the correct answer from several options. Learning common naming patterns can make that recognition much easier.
From our experience teaching pharmacy technicians over the past decade, we strongly recommend starting your study of the Top 200 drugs by following this structured approach:
- Drug class suffixes – learn common suffixes first. This means you bulk learn most of the Top 200 drugs in a much more structured format.
- Learn exceptions – some of these suffixes have exceptions. For instance, nystatin is an antifungal drug and not a HMG-CoA reductase inhibitor (such as atorvastatin, simvastatin, or rosuvastatin). Review our full table of exceptions below.
- Study the remaining drugs – with the major drug classes and exceptions covered, you can now spend your time learning those drugs that don’t fit any neat pattern.
This step-by-step approach ensures there is a logical approach to your study. It yields the best outcome when studying these medicines and it forms a backbone onto which you can then learn side effects, mechanisms of action, and key drug interactions.
You can also start with brand and generic names that share a clear connection:
- Clozaril — clozapine: an atypical antipsychotic.
- Diflucan — fluconazole: an azole antifungal.
- Haldol — haloperidol: an antipsychotic.
Some brand names can also provide clues about a medicine’s purpose. Glucophage, for example, was a brand name for metformin. Its name combines ideas associated with glucose and “eating” or consuming, reflecting metformin’s role in reducing blood glucose. Although Glucophage has been discontinued, the example still demonstrates how breaking down a memorable brand name can support recall.
Not every medicine has an obvious brand–generic connection. For these drugs, create a short personal association that connects the brand name, generic name, class, or indication. The association does not need to explain the drug scientifically—it simply needs to help you remember the correct information.
For example, Levitra is a brand name for vardenafil, a PDE-5 inhibitor used to treat erectile dysfunction. You might associate the beginning of Levitra with levitate, meaning “to rise.” This creates a simple link between the brand name and its primary use. You can then connect vardenafil with other drugs ending in -afil, including sildenafil and tadalafil. Recognizing the -afil suffix helps identify these medicines as PDE-5 inhibitors, allowing you to learn several related drugs as a group instead of treating each name as an isolated fact.
This same approach can be applied across the Top 200:
- Group medications by therapeutic class.
- Learn useful suffixes such as -pril, -sartan, -statin, and -prazole.
- Connect brand and generic names where a recognizable pattern exists.
- Create personal memory associations for drugs that do not follow a clear pattern.
- Review the information regularly rather than attempting to memorize everything at once.
Flashcards are particularly helpful here because they encourage active recall and repeat exposure. Each card can connect a drug’s brand and generic names with its class, indication, major adverse effects, and important interactions.
Remember – the aim is not to memorize 200 unrelated sets of facts. By organizing medications into classes and repeatedly reviewing their shared characteristics, you can build a structured foundation that makes individual drug names considerably easier to learn and retain.
The following Top 200 medications list has been updated to reflect changes based on the following three criteria:
- Current US prescribing frequency data
- Relevance to the 2026 – 2027 PTCE knowledge domains
- Practical importance, including controlled substances, insulin, anticoagulants, emergency drugs and common hospital medications
Rather than presenting the Top 200 drugs as one long list, we organize these medications by body system and primary therapeutic use. This gives your study a clearer structure and makes it easier to connect each medication with the conditions it commonly treats. Below these Top 200 drugs you can also separately find our controlled medications that appear on the Top 200.
This is the Top 200 drug list used throughout our online course. As a member, you’ll study each medication in greater detail, including its brand and generic names, drug class, indications, mechanism of action, common side effects, important interactions, contraindications, and key warnings. We organize this information into clear categories and use practical memory techniques to make the Top 200 easier to learn, understand, and recall for the PTCE.
Test your knowledge of these medications with our Top 200 Drugs Quiz.


| Drug(s) | Brand | Type of drug / purpose |
| Amiodarone | Pacerone | Antiarrhythmic used for serious abnormal heart rhythms |
| Amlodipine | Norvasc | Calcium channel blocker for hypertension and angina |
| Apixaban | Eliquis | Factor Xa inhibitor used to prevent and treat blood clots |
| Aspirin | Bayer | NSAID and antiplatelet drug used for pain or cardiovascular protection |
| Atenolol | Tenormin | Beta blocker for hypertension and angina |
| Atorvastatin | Lipitor | Statin used to lower LDL cholesterol and cardiovascular risk |
| Carvedilol | Coreg | Alpha/beta blocker for heart failure and hypertension |
| Chlorthalidone | Thalitone | Thiazide-like diuretic for hypertension |
| Clonidine | Catapres | Central alpha-2 agonist for hypertension |
| Clopidogrel | Plavix | P2Y12 inhibitor used to prevent blood clots |
| Digoxin | Lanoxin | Cardiac glycoside for heart failure and atrial fibrillation |
| Diltiazem | Cardizem CD | Calcium channel blocker for hypertension, angina and arrhythmias |
| Enoxaparin | Lovenox | Low-molecular-weight heparin used to prevent and treat clots |
| Evolocumab | Repatha | PCSK9 inhibitor used to lower LDL cholesterol |
| Ezetimibe | Zetia | Cholesterol-absorption inhibitor |
| Fenofibrate | Tricor | Fibrate used primarily to lower triglycerides |
| Furosemide | Lasix | Loop diuretic for edema, heart failure and hypertension |
| Heparin | Primarily generic | Anticoagulant used to prevent and treat blood clots |
| Hydralazine | Primarily generic | Direct vasodilator for hypertension and heart failure |
| Hydrochlorothiazide | Microzide | Thiazide diuretic for hypertension and edema |
| Isosorbide mononitrate | Primarily generic | Long-acting nitrate used to prevent angina |
| Lisinopril | Zestril | ACE inhibitor for hypertension, heart failure and kidney protection |
| Lisinopril/ hydrochlorothiazide | Zestoretic | ACE inhibitor and thiazide combination for hypertension |
| Losartan | Cozaar | ARB for hypertension and kidney protection |
| Losartan/ hydrochlorothiazide | Hyzaar | ARB and thiazide combination for hypertension |
| Metoprolol succinate | Toprol-XL | Extended-release beta blocker for hypertension and heart failure |
| Metoprolol tartrate | Lopressor | Immediate-release beta blocker for hypertension and cardiac conditions |
| Nifedipine | Procardia XL | Calcium channel blocker for hypertension and angina |
| Nitroglycerin | Nitrostat | Short-acting nitrate used to relieve angina |
| Olmesartan | Benicar | ARB for hypertension |
| Potassium chloride | Klor-Con | Electrolyte replacement used to prevent or treat hypokalemia |
| Propranolol | Inderal LA | Nonselective beta blocker for cardiovascular and neurologic conditions |
| Rivaroxaban | Xarelto | Factor Xa inhibitor used to prevent and treat blood clots |
| Rosuvastatin | Crestor | Statin used to lower cholesterol and cardiovascular risk |
| Sacubitril/ valsartan | Entresto | ARNI combination used for heart failure |
| Simvastatin | Zocor | Statin used to lower cholesterol |
| Spironolactone | Aldactone | Potassium-sparing diuretic and aldosterone antagonist |
| Valsartan | Diovan | ARB for hypertension and heart failure |
| Verapamil | Verelan | Calcium channel blocker for hypertension, angina and arrhythmias |
| Warfarin | Jantoven | Vitamin K antagonist used to prevent and treat blood clots |


| Drug(s) | Brand | Type of drug / purpose |
| Alendronate | Fosamax | Bisphosphonate used to prevent and treat osteoporosis |
| Allopurinol | Zyloprim | Xanthine oxidase inhibitor used to prevent gout |
| Colchicine | Colcrys | Antigout anti-inflammatory used for gout attacks and prevention |
| Cyanocobalamin | Nascobal | Vitamin B12 replacement |
| Dapagliflozin | Farxiga | SGLT2 inhibitor for diabetes, heart failure and kidney disease |
| Denosumab | Prolia | RANKL inhibitor used to treat osteoporosis |
| Dulaglutide | Trulicity | GLP-1 receptor agonist for type 2 diabetes |
| Empagliflozin | Jardiance | SGLT2 inhibitor for diabetes, heart failure and kidney disease |
| Ferrous sulfate | Feosol | Iron supplement used to treat iron-deficiency anemia |
| Glimepiride | Amaryl | Sulfonylurea used for type 2 diabetes |
| Glipizide | Glucotrol XL | Sulfonylurea used for type 2 diabetes |
| Insulin aspart | NovoLog | Rapid-acting insulin |
| Insulin degludec | Tresiba | Ultra-long-acting basal insulin |
| Insulin glargine | Lantus | Long-acting basal insulin |
| Insulin lispro | Humalog | Rapid-acting insulin |
| Levothyroxine | Synthroid | Thyroid hormone replacement for hypothyroidism |
| Metformin | Primarily generic | Biguanide and first-line treatment for type 2 diabetes |
| NPH insulin | Humulin N | Intermediate-acting insulin |
| Pioglitazone | Actos | Thiazolidinedione used for type 2 diabetes |
| Regular insulin | Humulin R | Short-acting insulin |
| Semaglutide | Ozempic | GLP-1 receptor agonist for diabetes and weight management |
| Sitagliptin | Januvia | DPP-4 inhibitor used for type 2 diabetes |
| Testosterone | AndroGel | Androgen replacement for testosterone deficiency |
| Tirzepatide | Mounjaro | GIP/GLP-1 receptor agonist for diabetes and weight management |


| Drug(s) | Brand | Type of drug / purpose |
| Alprazolam | Xanax | Benzodiazepine used for anxiety and panic disorder |
| Amitriptyline | Primarily generic | Tricyclic antidepressant also used for neuropathic pain |
| Aripiprazole | Abilify | Atypical antipsychotic for schizophrenia, bipolar disorder and depression |
| Atomoxetine | Strattera | Nonstimulant treatment for ADHD |
| Bupropion | Wellbutrin XL | NDRI antidepressant also used for smoking cessation |
| Buspirone | Primarily generic | Nonbenzodiazepine anxiolytic for generalized anxiety |
| Carbamazepine | Tegretol | Anticonvulsant used for seizures and trigeminal neuralgia |
| Carbidopa/ levodopa | Sinemet | Dopaminergic combination used for Parkinson disease |
| Citalopram | Celexa | SSRI antidepressant |
| Clonazepam | Klonopin | Benzodiazepine for seizures and panic disorder |
| Clozapine | Clozaril | Atypical antipsychotic for treatment-resistant schizophrenia |
| Divalproex sodium | Depakote | Anticonvulsant and mood stabilizer |
| Donepezil | Aricept | Acetylcholinesterase inhibitor for Alzheimer disease |
| Duloxetine | Cymbalta | SNRI for depression, anxiety and neuropathic pain |
| Escitalopram | Lexapro | SSRI for depression and anxiety |
| Fluoxetine | Prozac | SSRI for depression and several anxiety-related disorders |
| Gabapentin | Neurontin | Anticonvulsant also used for neuropathic pain |
| Lamotrigine | Lamictal | Anticonvulsant and bipolar maintenance treatment |
| Levetiracetam | Keppra | Anticonvulsant used to prevent seizures |
| Lisdexamfetamine | Vyvanse | CNS stimulant for ADHD and binge-eating disorder |
| Lithium | Lithobid | Mood stabilizer used primarily for bipolar disorder |
| Lorazepam | Ativan | Benzodiazepine for anxiety, seizures and sedation |
| Memantine | Namenda | NMDA antagonist for moderate-to-severe Alzheimer disease |
| Methylphenidate | Ritalin | CNS stimulant for ADHD and narcolepsy |
| Mixed amphetamine salts | Adderall | CNS stimulant used for ADHD |
| Olanzapine | Zyprexa | Atypical antipsychotic for schizophrenia and bipolar disorder |
| Paroxetine | Paxil | SSRI for depression and anxiety disorders |
| Phenytoin | Dilantin | Anticonvulsant used to prevent seizures |
| Pregabalin | Lyrica | Anticonvulsant used for neuropathic pain and fibromyalgia |
| Quetiapine | Seroquel | Atypical antipsychotic for schizophrenia and bipolar disorder |
| Rimegepant | Nurtec ODT | CGRP antagonist for acute treatment and prevention of migraine |
| Risperidone | Risperdal | Atypical antipsychotic |
| Sertraline | Zoloft | SSRI for depression and anxiety-related disorders |
| Sumatriptan | Imitrex | Triptan used for acute migraine attacks |
| Topiramate | Topamax | Anticonvulsant also used for migraine prevention |
| Trazodone | Primarily generic | Serotonin-modulating antidepressant commonly used for insomnia |
| Venlafaxine | Effexor XR | SNRI for depression and anxiety disorders |
| Zolpidem | Ambien | Sedative-hypnotic used for insomnia |


| Drug(s) | Brand | Type of drug / purpose |
| Acetaminophen | Tylenol | Nonopioid analgesic and fever reducer |
| Baclofen | Primarily generic | Skeletal muscle relaxant used for spasticity |
| Celecoxib | Celebrex | COX-2 selective NSAID for pain and inflammation |
| Cyclobenzaprine | Primarily generic | Skeletal muscle relaxant for acute muscle spasms |
| Diclofenac | Voltaren | NSAID for pain and inflammation |
| Fentanyl | Duragesic | Potent opioid analgesic for severe pain |
| Hydrocodone/ acetaminophen | Norco | Opioid and nonopioid analgesic combination |
| Ibuprofen | Advil | NSAID used for pain, fever and inflammation |
| Ketorolac | Toradol | NSAID used for short-term treatment of moderate-to-severe pain |
| Meloxicam | Mobic | NSAID for arthritis-related pain and inflammation |
| Methadone | Methadose | Opioid used for severe pain and opioid use disorder |
| Methocarbamol | Robaxin | Skeletal muscle relaxant |
| Morphine | MS Contin | Opioid analgesic for severe pain |
| Naloxone | Narcan | Opioid antagonist used to reverse opioid overdose |
| Naproxen | Aleve | NSAID for pain and inflammation |
| Oxycodone | OxyContin | Opioid analgesic for moderate-to-severe pain |
| Oxycodone/ acetaminophen | Percocet | Opioid and nonopioid analgesic combination |
| Tramadol | Ultram | Opioid analgesic for moderate-to-severe pain |


| Drug(s) | Brand | Type of drug / purpose |
| Acyclovir | Zovirax | Antiviral for herpesvirus infections |
| Amoxicillin | Amoxil | Aminopenicillin antibiotic |
| Amoxicillin/ clavulanate | Augmentin | Penicillin and beta-lactamase inhibitor combination |
| Azithromycin | Zithromax | Macrolide antibiotic |
| Cefdinir | Primarily generic | Third-generation cephalosporin antibiotic |
| Ceftriaxone | Rocephin | Injectable third-generation cephalosporin |
| Cephalexin | Keflex | First-generation cephalosporin antibiotic |
| Ciprofloxacin | Cipro | Fluoroquinolone antibiotic |
| Clindamycin | Cleocin | Lincosamide antibiotic |
| Doxycycline | Doryx | Tetracycline antibiotic |
| Emtricitabine/ tenofovir | Truvada | NRTI combination for HIV treatment and PrEP |
| Fluconazole | Diflucan | Azole antifungal |
| Levofloxacin | Primarily generic | Fluoroquinolone antibiotic |
| Metronidazole | Flagyl | Nitroimidazole antimicrobial and antiprotozoal |
| Mupirocin | Bactroban | Topical antibiotic |
| Nirmatrelvir/ ritonavir | Paxlovid | Antiviral combination used to treat COVID-19 |
| Nitrofurantoin | Macrobid | Urinary anti-infective primarily used for uncomplicated UTIs |
| Nystatin | Primarily generic | Polyene antifungal used for Candida infections |
| Oseltamivir | Tamiflu | Neuraminidase inhibitor used for influenza |
| Penicillin V potassium | Pen-Vee K | Natural penicillin antibiotic |
| Piperacillin/ tazobactam | Zosyn | Broad-spectrum penicillin and beta-lactamase inhibitor |
| Sulfamethoxazole/ trimethoprim | Bactrim DS | Sulfonamide combination antibiotic |
| Valacyclovir | Valtrex | Antiviral for herpesvirus infections |
| Vancomycin | Vancocin | Glycopeptide antibiotic for serious gram-positive infections |


| Drug(s) | Brand | Type of drug / purpose |
| Albuterol | Ventolin HFA | Short-acting beta-2 agonist rescue bronchodilator |
| Albuterol/ ipratropium | DuoNeb | Short-acting bronchodilator combination for COPD |
| Benzonatate | Tessalon | Nonopioid cough suppressant |
| Budesonide/ formoterol | Symbicort | Inhaled corticosteroid and LABA combination |
| Cetirizine | Zyrtec | Second-generation antihistamine for allergies |
| Dupilumab | Dupixent | IL-4/IL-13 inhibitor for eczema, asthma and related conditions |
| Epinephrine | EpiPen | Adrenergic agonist used for anaphylaxis |
| Fluticasone nasal | Flonase | Intranasal corticosteroid for allergic rhinitis |
| Fluticasone/ salmeterol | Advair Diskus | Inhaled corticosteroid and LABA combination |
| Fluticasone/ umeclidinium/ vilanterol | Trelegy Ellipta | ICS/LAMA/LABA inhaler for COPD and asthma |
| Hydroxyzine | Vistaril | First-generation antihistamine used for itching and anxiety |
| Loratadine | Claritin | Second-generation antihistamine for allergies |
| Methylprednisolone | Medrol | Systemic corticosteroid for inflammatory conditions |
| Montelukast | Singulair | Leukotriene receptor antagonist for asthma and allergies |
| Prednisolone | Orapred | Systemic corticosteroid for inflammatory conditions |
| Prednisone | Rayos; generic | Systemic corticosteroid for inflammation and immune conditions |
| Tiotropium | Spiriva | Long-acting muscarinic antagonist for COPD and asthma |


| Drug(s) | Brand | Type of drug / purpose |
| Dicyclomine | Bentyl | Anticholinergic antispasmodic for irritable bowel syndrome |
| Docusate | Colace | Stool softener for constipation |
| Esomeprazole | Nexium | Proton-pump inhibitor for GERD and acid-related disorders |
| Famotidine | Pepcid | H2 blocker for heartburn and acid-related disorders |
| Lansoprazole | Prevacid | Proton-pump inhibitor |
| Linaclotide | Linzess | Guanylate cyclase-C agonist for IBS-C and chronic constipation |
| Loperamide | Imodium A-D | Antidiarrheal that reduces intestinal motility |
| Mesalamine | Lialda | 5-ASA anti-inflammatory for ulcerative colitis |
| Metoclopramide | Reglan | Prokinetic and antiemetic for gastroparesis and nausea |
| Omeprazole | Prilosec | Proton-pump inhibitor |
| Ondansetron | Zofran | 5-HT3 antagonist antiemetic |
| Pantoprazole | Protonix | Proton-pump inhibitor |
| Polyethylene glycol 3350 | MiraLAX | Osmotic laxative |
| Promethazine | Phenergan | Antihistamine and antiemetic |
| Senna | Senokot | Stimulant laxative |


| Drug(s) | Brand | Type of drug / purpose |
| Estradiol | Estrace | Estrogen used for menopausal symptoms and hormone replacement |
| Ethinyl estradiol/ etonogestrel | NuvaRing | Combined hormonal contraceptive vaginal ring |
| Ethinyl estradiol/ norethindrone | Junel Fe | Combined oral contraceptive |
| Ethinyl estradiol/ norgestimate | Tri-Sprintec | Combined oral contraceptive |
| Finasteride | Proscar | 5-alpha-reductase inhibitor for benign prostatic hyperplasia |
| Mirabegron | Myrbetriq | Beta-3 agonist for overactive bladder |
| Norethindrone | Camila | Progestin-only oral contraceptive |
| Norgestrel | Opill | OTC progestin-only oral contraceptive |
| Oxybutynin | Ditropan XL | Anticholinergic for overactive bladder |
| Sildenafil | Viagra | PDE5 inhibitor for erectile dysfunction |
| Tadalafil | Cialis | PDE5 inhibitor for erectile dysfunction and BPH |
| Tamsulosin | Flomax | Alpha-1 blocker for benign prostatic hyperplasia |


| Drug(s) | Brand | Type of drug / purpose |
| Adalimumab | Humira | TNF inhibitor for inflammatory autoimmune diseases |
| Brimonidine | Alphagan P | Alpha-2 agonist used to lower intraocular pressure |
| Clobetasol | Temovate | Super-high-potency topical corticosteroid |
| Cyclosporine | Restasis; Neoral | Calcineurin inhibitor used for dry eye or systemic immunosuppression |
| Hydroxychloroquine | Plaquenil | Antimalarial and DMARD for lupus and rheumatoid arthritis |
| Latanoprost | Xalatan | Prostaglandin analog used for glaucoma |
| Meclizine | Antivert | Antihistamine used for vertigo and motion sickness |
| Methotrexate | Otrexup | Antimetabolite and DMARD for cancer and autoimmune conditions |
| Tacrolimus | Prograf | Calcineurin inhibitor used to prevent transplant rejection |
| Timolol ophthalmic | Timoptic | Ophthalmic beta blocker used for glaucoma |
| Tretinoin | Retin-A | Topical retinoid for acne and photoaged skin |
| Triamcinolone | Kenalog | Corticosteroid used for inflammatory skin and other conditions |
Controlled Medications on the Top 200 List.
This section identifies the commonly prescribed controlled medications included in the Top 200, along with their federal schedules, brand names, and drug classes. Use it to recognize which medicines are subject to additional prescribing, dispensing, storage, and recordkeeping requirements.
| Sch. | Generic name | Brand name | Drug class |
| II | Amphetamine/ dextroamphetamine |
Adderall, Adderall XR | CNS stimulant |
| II | Lisdexamfetamine | Vyvanse | CNS stimulant |
| II | Methylphenidate | Ritalin, Concerta | CNS stimulant |
| II | Dexmethylphenidate | Focalin | CNS stimulant |
| II | Hydrocodone/ acetaminophen |
Norco | Opioid/non-opioid analgesic combination |
| II | Oxycodone | OxyContin, Roxicodone | Opioid analgesic |
| II | Oxycodone/ acetaminophen |
Percocet | Opioid/non-opioid analgesic combination |
| II | Morphine | MS Contin | Opioid analgesic |
| II | Fentanyl | Duragesic | Opioid analgesic |
| II | Hydromorphone | Dilaudid | Opioid analgesic |
| II | Methadone | Methadose | Opioid analgesic; opioid-use-disorder medication |
| III | Buprenorphine/ naloxone |
Suboxone | Partial opioid agonist/opioid antagonist combination |
| III | Buprenorphine | Subutex | Partial opioid agonist |
| III | Acetaminophen/ codeine |
Tylenol with Codeine No. 3 | Opioid/non-opioid analgesic combination |
| III | Testosterone | AndroGel, Depo-Testosterone | Androgen/anabolic steroid |
| IV | Alprazolam | Xanax | Benzodiazepine |
| IV | Clonazepam | Klonopin | Benzodiazepine |
| IV | Lorazepam | Ativan | Benzodiazepine |
| IV | Diazepam | Valium | Benzodiazepine |
| IV | Temazepam | Restoril | Benzodiazepine |
| IV | Zolpidem | Ambien | Nonbenzodiazepine sedative-hypnotic |
| IV | Eszopiclone | Lunesta | Nonbenzodiazepine sedative-hypnotic |
| IV | Tramadol | Ultram | Opioid analgesic |
| IV | Phentermine | Adipex-P | Sympathomimetic appetite suppressant |
| IV | Carisoprodol | Soma | Skeletal muscle relaxant |
| IV | Modafinil | Provigil | Wakefulness-promoting agent |
| V | Pregabalin | Lyrica | Gabapentinoid; antiseizure medication |
PTCE Drug Class Suffixes.
Throughout your study of the Top 200 medications, you may have already come across some common themes. For instance, drugs such as bisopolol, labetalol, and metoprolol all sound the same because they share a common suffix, -lol. You can use these common suffixes as the foundation of your study of the Top 200 drugs. Yes, there are exceptions (which you can find below), but as general rules, they are very effective at condensing many medicines into much more manageable study chunks.
Below you can find the top 50 medication suffixes to help you in your study preparation. Use this table as the basis to start your study of the Top 200 drugs.
| Drug suffix | Drug class and examples | Main indications |
| -pril | ACE inhibitors: lisinopril, enalapril, benazepril | Hypertension, heart failure and kidney protection |
| -sartan | Angiotensin II receptor blockers: losartan, valsartan, olmesartan | Hypertension, heart failure and kidney protection |
| -lol | Beta blockers: metoprolol, atenolol, propranolol | Hypertension, angina, arrhythmias and heart failure |
| -dipine | Dihydropyridine calcium-channel blockers: amlodipine, nifedipine | Hypertension and angina |
| -zosin | Alpha₁ blockers: doxazosin, prazosin, terazosin | Hypertension and benign prostatic hyperplasia |
| -statin | HMG-CoA reductase inhibitors: atorvastatin, rosuvastatin, simvastatin | High cholesterol and prevention of cardiovascular events |
| -fibrate | Fibrates: fenofibrate | High triglycerides and mixed dyslipidemia |
| -semide | Loop diuretics: furosemide, torsemide | Edema, heart failure and hypertension |
| -thiazide | Thiazide diuretics: hydrochlorothiazide | Hypertension and edema |
| -gliflozin | SGLT2 inhibitors: empagliflozin, dapagliflozin | Type 2 diabetes, heart failure and chronic kidney disease |
| -gliptin | DPP-4 inhibitors: sitagliptin, linagliptin | Type 2 diabetes |
| -glutide | GLP-1 receptor agonists: semaglutide, dulaglutide, liraglutide | Type 2 diabetes, weight management and cardiovascular-risk reduction |
| -glinide | Meglitinides: repaglinide, nateglinide | Type 2 diabetes and control of mealtime blood glucose |
| -glitazone | Thiazolidinediones: pioglitazone | Type 2 diabetes |
| -prazole | Proton-pump inhibitors: omeprazole, pantoprazole, esomeprazole | GERD, peptic ulcers and other acid-related disorders |
| -tidine | H₂-receptor antagonists: famotidine, cimetidine | Heartburn, GERD and peptic ulcers |
| -setron | 5-HT₃ antagonists: ondansetron | Prevention and treatment of nausea and vomiting |
| -triptan | 5-HT₁B/₁D agonists: sumatriptan, rizatriptan | Acute migraine treatment |
| -gepant | CGRP-receptor antagonists: ubrogepant, rimegepant | Acute treatment or prevention of migraine |
| -cillin | Penicillins: amoxicillin, ampicillin, dicloxacillin | Susceptible bacterial infections |
| -cycline | Tetracyclines: doxycycline, minocycline | Bacterial infections, acne and rosacea |
| -floxacin | Fluoroquinolones: ciprofloxacin, levofloxacin | Selected bacterial infections |
| -thromycin | Macrolide antibiotics: azithromycin, clarithromycin, erythromycin | Respiratory, skin and other bacterial infections |
| -conazole | Azole antifungals: fluconazole, itraconazole | Fungal infections |
| -vir | Antiviral medicines: acyclovir, valacyclovir, oseltamivir | Viral infections such as herpes, shingles and influenza |
| -lukast | Leukotriene-receptor antagonists: montelukast | Asthma maintenance and allergic rhinitis |
| -terol | Beta₂-agonist bronchodilators: albuterol, salmeterol, formoterol | Asthma and COPD |
| -tropium | Inhaled antimuscarinics: ipratropium, tiotropium | COPD and asthma maintenance |
| -casone | Inhaled or nasal corticosteroid pattern: fluticasone | Asthma, COPD and allergic rhinitis |
| -tadine | Second-generation antihistamine pattern: loratadine, desloratadine | Allergic rhinitis and hives |
| -pam / -lam | Benzodiazepines: diazepam, lorazepam, alprazolam | Anxiety, seizures, insomnia and procedural sedation |
| -triptyline | Tricyclic antidepressants: amitriptyline, nortriptyline | Depression, neuropathic pain and migraine prevention |
| -pram | SSRI pattern: citalopram, escitalopram | Depression and anxiety disorders |
| -faxine | SNRIs: venlafaxine, desvenlafaxine | Depression and anxiety disorders |
| -pezil | Acetylcholinesterase inhibitor: donepezil | Symptoms of Alzheimer disease |
| -dopa | Dopamine precursor: levodopa | Parkinson disease |
| -caine | Local anesthetic pattern: lidocaine, bupivacaine | Local and regional anesthesia |
| -profen | NSAIDs: ibuprofen, ketoprofen | Pain, fever and inflammation |
| -coxib | COX-2-selective NSAIDs: celecoxib | Pain and inflammatory arthritis |
| -cam | Oxicam NSAIDs: meloxicam, piroxicam | Arthritis and musculoskeletal pain |
| -codone | Opioid analgesics: hydrocodone, oxycodone | Moderate to severe pain |
| -xaban | Direct factor Xa inhibitors: apixaban, rivaroxaban | Prevention and treatment of blood clots and stroke prevention in atrial fibrillation |
| -gatran | Direct thrombin inhibitor: dabigatran | Prevention and treatment of blood clots and stroke prevention in atrial fibrillation |
| -grel | P2Y₁₂ antiplatelet drugs: clopidogrel, prasugrel | Prevention of heart attack, stroke and stent thrombosis |
| -parin | Low-molecular-weight heparins: enoxaparin | Prevention and treatment of blood clots |
| -ronate | Bisphosphonates: alendronate, risedronate | Osteoporosis |
| -afil | PDE-5 inhibitors: sildenafil, tadalafil | Erectile dysfunction, pulmonary hypertension and benign prostatic hyperplasia |
| -asteride | 5-alpha-reductase inhibitors: finasteride, dutasteride | Benign prostatic hyperplasia and male-pattern hair loss |
| -gron | Beta₃-adrenergic agonists: mirabegron, vibegron | Overactive bladder |
| -mab | Monoclonal antibodies: adalimumab, evolocumab | Uses vary by drug and include inflammatory diseases and high cholesterol |
Most Common Misleading Drug Suffix Exceptions.
As we learned earlier, not all drugs follow a neat naming path. For instance, not all drugs that end in -statin are statins that lower blood cholesterol.
In this table we have compiled the most important drug-suffix exceptions for your PTCE exam study.
| Naming pattern | Major examples and exceptions | PTCE takeaway |
| -statin / -vastatin | Atorvastatin, rosuvastatin and simvastatin lower cholesterol. Nystatin is a polyene antifungal. Somatostatin is a peptide that inhibits growth hormone. Synthetic version of this peptide are used in the treatment of acromegaly (such as octreotide). Pentostatin is a chemotherapy drug used to treat a form of leukemia. | Look for the complete -vastatin ending when identifying HMG-CoA reductase inhibitors. |
| -mycin / -micin | Azithromycin, clarithromycin and erythromycin are macrolides. Clindamycin is a lincosamide. Vancomycin is a glycopeptide. Gentamicin and tobramycin are aminoglycosides. | -mycin alone does not identify one antibiotic class. Learn the major antibiotics individually. |
| -azole | Fluconazole and ketoconazole are antifungals; metronidazole is an antibacterial and antiprotozoal; albendazole is an anthelmintic; omeprazole is a proton-pump inhibitor. | Read the fuller pattern: -conazole, -nidazole, -bendazole or -prazole. |
| -prazole | Omeprazole and pantoprazole are proton-pump inhibitors. Aripiprazole is an antipsychotic drug. | The letters before -prazole matter; not every apparent -prazole drug is an acid reducer. |
| -tidine vs. -tadine | Famotidine is an H₂-receptor antagonist. Loratadine and desloratadine are antihistamines. | One letter changes the class: -tidine suggests an H₂ blocker, while -tadine suggests an antihistamine. |
| -olone | Prednisolone, methylprednisolone and triamcinolone are corticosteroids. Nandrolone and oxandrolone are anabolic steroids and Schedule III controlled substances. | -olone suggests a steroid structure but does not distinguish corticosteroids from anabolic steroids. |
| -olol | Metoprolol, atenolol and propranolol are beta blockers. Carvedilol and labetalol are also beta blockers but do not end in -olol and additionally block alpha₁ receptors. | Most -olol drugs are beta blockers, but the class contains important reverse exceptions. |
| -oxetine | Fluoxetine and paroxetine are SSRIs; duloxetine is an SNRI; atomoxetine is a selective norepinephrine reuptake inhibitor used for ADHD. | The -oxetine ending does not identify one antidepressant class—and atomoxetine is not classified as an antidepressant. |
| -apine / -azine | Quetiapine, olanzapine and clozapine are antipsychotics, but mirtazapine is an antidepressant. Chlorpromazine is an antipsychotic, promethazine is an antihistamine, and sulfasalazine is an anti-inflammatory drug. | These broad endings are unreliable by themselves; learn the individual drug and its class. |
| -done / -idone | Methadone is an opioid; trazodone is an antidepressant; risperidone is an antipsychotic; ondansetron is an antiemetic. | The final few letters are too broad to classify these drugs. Look for the complete name or fuller stem. |
| -dipine | Amlodipine and nifedipine are dihydropyridine calcium-channel blockers. Diltiazem and verapamil are calcium-channel blockers without the suffix and can significantly slow heart rate. | -dipine identifies one subclass, not every calcium-channel blocker. |
| -pine / -dipine | Olanzapine and clozapine are antipsychotic drugs. Amlodipine and nifedipine are calcium channel blockers used to treat hypertension. | Always consider the fuller suffix to help you recall these differences; in this case: -zapine vs dipine. |
Frequently Asked Questions.
Remember, there is no official “Top 200 drugs” list. This is a construct that is used to help students learn the most commonly prescribed and dispensed medicines. It also changes year-to-year because prescription volumes and medication sales can vary. Our list has been compiled from the latest prescribing data, and we update this list every 6-months to ensure it remains current for your exam preparation.
We always recommend our pharmacy technicians to start with drug classes that share a common medication suffix. Think of ACE inhibitors (-pril), beta blockers (-lol), and statins (-statin), for example. These three suffixes alone help you to learn over 20 widely dispensed medications. There are about fifty common suffixes within the broader Top 200 drugs. Learning these fifty help to cement most of the memorization. Then, you can focus on the exceptions to the rule and those other drugs that do not neatly fit in. This structured approach to studying the Top 200 drugs has considerably higher success rate.
Our course provides a structured approach to study the medications you need to know. It includes Top 200 drug study materials, flashcards, practice questions, and lessons covering generic and brand names, as well as key pharmacology covering therapeutic classes, indications, common side effects, and major interactions. This means you can learn the Top 200 drugs without needing to piece together multiple resources. Our course has everything you need in one place.
This is a great question because, no matter which study approach is used, recalling drug suffixes can still be difficult. That’s why we recommend using flashcards. Constant repetition of the key details of each drug class makes learning the Top 200 drugs far simpler, and far more organized. Don’t be afraid to come up with original and creative ways of memorizing drug classes. The more creative, the more memorable it becomes! As long as you are consistent with study, your knowledge will grow over time.
The time required varies according to your existing knowledge, practical experience to date, and study schedule, but most pharmacy technicians should expect to study the list consistently over several weeks rather than trying to memorize it all at once. Learning a small number of medications each day — and regularly reviewing their brand and generic names, classes, uses, and key safety information — is generally more effective for long-term recall. It’s important not to rush your study. From our experience, 8-16 weeks is typically a good benchmark depending on the factors listed above.
Yes
Combination medications appear less commonly, but they are tested. Consult our Top 200 drugs list above for the most common examples.
No.
Pharmacy technicians are not required to learn drug strengths and dosages. These are clinical factors that only pharmacists and prescribers would be required to know.






























