Missouri State Requirements

You must apply for registration with the Missouri Board of Pharmacy before working as a pharmacy technician. However, Missouri allows you to begin work while your application is pending once the Board has received your completed application, required fee, and proof of fingerprint submission. You must keep proof of the submitted application at your workplace and stop working immediately if registration is refused.

Missouri has one pharmacy technician registration tier. A “qualified pharmacy technician” is a registered technician who meets additional certification, training, competency, and experience requirements for certain expanded duties; it is not a separate state registration.

Applicants must be at least the legal working age under Missouri law. Missouri’s pharmacy technician requirements do not establish a separate fixed minimum age.

Missouri does not require a high school diploma, GED, or equivalent qualification for standard pharmacy technician registration.

Missouri does not require a specific training program or number of training hours for initial registration. Before performing delegated duties, you must be properly trained and competent to complete those duties safely.

PTCB, NHA/ExCPT, or another national certification is not required for standard registration. Active certification from an organization accredited by the National Commission for Certifying Agencies is required for certain expanded activities, including vaccine and medication administration.

Pharmacy technician applicants must complete a state and federal fingerprint-based criminal-history background check through the Missouri State Highway Patrol and FBI. Note that proof of fingerprint submission must be provided as part of your application.

The current fingerprinting fee is $44, although the amount is subject to change. This fee is paid directly to the state-approved fingerprinting vendor.

New applications are submitted through the MOPRO online licensing portal. Missouri moved pharmacy technician applications to MOPRO effective August 4, 2025.

The initial pharmacy technician registration fee is $40. The fee is separate from fingerprinting and any applicable online-system charges.

Pharmacy technician registrations expire annually on May 31. Missouri law provides that a registration lapses and becomes invalid 30 days after its expiration date, but technicians should renew by May 31 to avoid an interruption in their authority to work.

The annual pharmacy technician renewal fee is $40. For the 2026 renewal cycle, there is a separate $12 MOPRO system user fee.

Under Missouri Revised Statutes § 338.010 and State Board of Pharmacy Rule 20 CSR 2220-6.050, pharmacists may delegate vaccine administration to qualified pharmacy technicians. You must hold current Missouri registration, maintain active national certification from an NCCA-accredited organization, have at least one year of registered or licensed pharmacy-technician experience, complete the required immunization training, hold qualifying CPR or BLS certification, and demonstrate competency in vaccine administration.

Rule 20 CSR 2220-6.040 also permits qualified pharmacy technicians to administer medications pursuant to a medical prescription order when they satisfy the applicable certification, experience, training, competency, and CPR or BLS requirements.